JAK3 抗体
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北京 101111
Quick Overview for JAK3 抗体 (ABIN634320)
抗原
See all JAK3 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- JAK3 antibody was raised using a synthetic peptide corresponding to a region with amino acids KLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELF
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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JAK3 Blocking Peptide, (ABIN939905), is also available for use as a blocking control in assays to test for specificity of this JAK3 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of JAK3 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- JAK3 (Janus Kinase 3 (JAK3))
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别名
- JAK3
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背景
- JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).
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分子量
- 125 kDa (MW of target protein)
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
抗原
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