PDGFB 抗体 (N-Term)
Quick Overview for PDGFB 抗体 (N-Term) (ABIN634264)
抗原
See all PDGFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- PDGFB antibody was raised against the N terminal of PDGFB
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纯化方法
- Affinity purified
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免疫原
- PDGFB antibody was raised using the N terminal of PDGFB corresponding to a region with amino acids NRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGD
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anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 20-241) antibody
PDGFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 155-210) antibodyPDGFB 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 84-199) antibodyPDGFB 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 1-241) antibodyPDGFB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (N-Term) antibodyPDGFB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (C-Term) antibodyVerified PDGFB 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 82-190) antibodyPDGFB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 82-190) antibodyPDGFB 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 21-241) antibodyPDGFB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Subunit B (PDGFB) (AA 212-241), (C-Term) antibodyPDGFB 适用: 人 WB, IF 宿主: 兔 Polyclonal RB2203 unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PDGFB Blocking Peptide, catalog no. 33R-6853, is also available for use as a blocking control in assays to test for specificity of this PDGFB antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PDGFB antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
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别名
- PDGFB
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背景
- PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.
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分子量
- 27 kDa (MW of target protein)
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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