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MCM10 抗体 (Middle Region)

The 兔 多克隆 anti-MCM10 antibody is suitable to detect MCM10 in samples from 人. It has been validated for WB.
产品编号 ABIN634085
发货至: 中国
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Quick Overview for MCM10 抗体 (Middle Region) (ABIN634085)

抗原

See all MCM10 抗体
MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

适用

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宿主

  • 24
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克隆类型

  • 25
多克隆

标记

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This MCM10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    特异性

    MCM10 antibody was raised against the middle region of MCM10

    纯化方法

    Affinity purified

    免疫原

    MCM10 antibody was raised using the middle region of MCM10 corresponding to a region with amino acids PKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERV
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    MCM10 Blocking Peptide, (ABIN5614695), is also available for use as a blocking control in assays to test for specificity of this MCM10 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM10 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

    别名

    MCM10

    背景

    This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding.

    分子量

    98 kDa (MW of target protein)

    途径

    Mitotic G1-G1/S Phases, DNA Replication
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