Manic Fringe 抗体 (C-Term)
Quick Overview for Manic Fringe 抗体 (C-Term) (ABIN633865)
抗原
See all Manic Fringe (MFNG) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            特异性
- MFNG antibody was raised against the C terminal of MFNG
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                                            纯化方法
- Affinity purified
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                                            免疫原
- MFNG antibody was raised using the C terminal of MFNG corresponding to a region with amino acids QLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYP
 
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                                            应用备注
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                        WB: 0.25 µg/mL
 Optimal conditions should be determined by the investigator.
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                                            说明
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                        MFNG Blocking Peptide, (ABIN5614739), is also available for use as a blocking control in assays to test for specificity of this MFNG antibody 
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MFNG antibody in PBS
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                                            浓度
- Lot specific
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                                            缓冲液
- PBS
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                                            注意事项
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                        Avoid repeated freeze/thaw cycles. 
 Dilute only prior to immediate use.
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                                            储存条件
- 4 °C/-20 °C
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                                            储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
 
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    - Manic Fringe (MFNG) (MFNG)
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                                            别名
- MFNG
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                                            背景
- MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
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                                            分子量
- 36 kDa (MW of target protein)
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                                            途径
- Notch Signaling
 抗原
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