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ube3a 抗体 (N-Term)

This anti-ube3a antibody is a 兔 多克隆 antibody detecting ube3a in WB. Suitable for 人.
产品编号 ABIN633810
发货至: 中国

Quick Overview for ube3a 抗体 (N-Term) (ABIN633810)

抗原

See all ube3a 抗体
ube3a (Ubiquitin Protein Ligase E3A (ube3a))

适用

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宿主

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克隆类型

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多克隆

标记

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This ube3a antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    UBE3 A antibody was raised against the N terminal Of Ube3

    纯化方法

    Affinity purified

    免疫原

    UBE3 A antibody was raised using the N terminal Of Ube3 corresponding to a region with amino acids SLQAKDEDKDEDEKEKAACSAAAMEEDSEASSSRIGDSSQGDNNLQKLGP
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    UBE3A Blocking Peptide, (ABIN5616878), is also available for use as a blocking control in assays to test for specificity of this UBE3A antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UBE0 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    ube3a (Ubiquitin Protein Ligase E3A (ube3a))

    别名

    UBE3A

    背景

    UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53.

    分子量

    101 kDa (MW of target protein)

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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