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CHMP4B 抗体 (Middle Region)

CHMP4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN633066
发货至: 中国
  • 抗原 See all CHMP4B 抗体
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 45
    • 22
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP4B antibody is un-conjugated
    应用范围
    • 20
    • 19
    • 18
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    Western Blotting (WB)
    特异性
    CHMP4 B antibody was raised against the middle region of CHMP4
    纯化方法
    Affinity purified
    免疫原
    CHMP4 B antibody was raised using the middle region of CHMP4 corresponding to a region with amino acids RKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH
    Top Product
    Discover our top product CHMP4B Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    CHMP4B Blocking Peptide, catalog no. 33R-8000, is also available for use as a blocking control in assays to test for specificity of this CHMP4B antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHMP0 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    别名
    CHMP4B (CHMP4B 产品)
    别名
    C20orf178 antibody, CHMP4A antibody, CTPP3 antibody, CTRCT31 antibody, SNF7 antibody, SNF7-2 antibody, Shax1 antibody, VPS32B antibody, Vps32-2 antibody, dJ553F4.4 antibody, 2010012F05Rik antibody, C76846 antibody, Snf7-2 antibody, RGD1309846 antibody, RGD1565889 antibody, CHMP4b antibody, chmp4b antibody, chmp4b.S antibody, CHMP4c antibody, c20orf178 antibody, wu:fc96b02 antibody, zgc:55566 antibody, charged multivesicular body protein 4B antibody, charged multivesicular body protein 4Ba antibody, charged multivesicular body protein 4B L homeolog antibody, charged multivesicular body protein 4Bb antibody, CHMP4B antibody, Chmp4b antibody, chmp4ba antibody, chmp4b.L antibody, chmp4bb antibody
    背景
    This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.
    分子量
    25 kDa (MW of target protein)
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