PPP4R2 抗体 (C-Term)
Quick Overview for PPP4R2 抗体 (C-Term) (ABIN632513)
抗原
See all PPP4R2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PPP4 R2 antibody was raised against the C terminal of PPP4 2
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纯化方法
- Affinity purified
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免疫原
- PPP4 R2 antibody was raised using the C terminal of PPP4 2 corresponding to a region with amino acids DSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PPP4R2 Blocking Peptide, (ABIN937563), is also available for use as a blocking control in assays to test for specificity of this PPP4R2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PPP0 2 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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别名
- PPP4R2
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背景
- PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
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分子量
- 47 kDa (MW of target protein)
抗原
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