PPP4R2 抗体 (C-Term)
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北京 101111
Quick Overview for PPP4R2 抗体 (C-Term) (ABIN2775552)
抗原
See all PPP4R2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PPP4R2 Antibody - C-terminal region
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序列
- DSRCTRQHCT EEDEEEDEEE EEESFMTSRE MIPERKNQEK ESDDALTVNE
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PPP4R2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2
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anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) antibody
PPP4R2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-360) antibodyPPP4R2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 228-254) antibodyPPP4R2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37606 unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 288-337) antibodyPPP4R2 适用: 人, 小鼠, 猴, 大鼠, Cow, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42719-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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别名
- PPP4R2
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背景
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Targeted Subunit: 2
Background Information: PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Gene Name: Protein phosphatase 4, regulatory subunit 2
Alternative Symbols: PP4R2
Protein Name: Serine/threonine-protein phosphatase 4 regulatory subunit 2
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分子量
- 47kDa
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基因ID
- 151987
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NCBI登录号
- NP_777567
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UniProt
- Q9NY27
抗原
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