PPP4R2 抗体 (Internal Region)
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- 抗原 See all PPP4R2 抗体
- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP4R2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- PPP4R2 Antibody detects endogenous levels of total PPP4R2.
- 预测反应
- Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PPP4R2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PPP4R2 Primary Antibody
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anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) antibody
PPP4R2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-360) antibodyPPP4R2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 288-337) antibodyPPP4R2 适用: 人, 小鼠, 猴, 大鼠, Cow, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
- 别名
- PPP4R2 (PPP4R2 产品)
- 别名
- PP4R2 antibody, BE691708 antibody, C230060M08Rik antibody, ppp4r2 antibody, fe11b04 antibody, wu:fe11b04 antibody, ppp4r2-B antibody, wu:fa17h08 antibody, wu:fc23g05 antibody, protein phosphatase 4 regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2a antibody, protein phosphatase 4 regulatory subunit 2 S homeolog antibody, protein phosphatase 4 regulatory subunit 2 L homeolog antibody, protein phosphatase 4, regulatory subunit 2b antibody, PPP4R2 antibody, Ppp4r2 antibody, ppp4r2a antibody, ppp4r2.S antibody, ppp4r2 antibody, ppp4r2.L antibody, ppp4r2b antibody
- 背景
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Description: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
Gene: PPP4R2
- 分子量
- 50 kDa
- 基因ID
- 151987
- UniProt
- Q9NY27
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