DMBT1 抗体 (N-Term)
Quick Overview for DMBT1 抗体 (N-Term) (ABIN632489)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- DMBT1 antibody was raised against the N terminal of DMBT1
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纯化方法
- Affinity purified
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免疫原
- DMBT1 antibody was raised using the N terminal of DMBT1 corresponding to a region with amino acids SWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWG
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anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibody
DMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 1701-1785) antibodyDMBT1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2008-2413) antibodyDMBT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) antibodyDMBT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2160-2192) antibodyDMBT1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB53896 unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DMBT1 Blocking Peptide, (ABIN5613222), is also available for use as a blocking control in assays to test for specificity of this DMBT1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DMBT1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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别名
- DMBT1
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背景
- Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
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分子量
- 258 kDa (MW of target protein)
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途径
- Activation of Innate immune Response
抗原
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