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DMBT1 抗体 (AA 1701-1785)

DMBT1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN670626
发货至: 中国
  • 抗原 See all DMBT1 抗体
    DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1701-1785
    适用
    • 15
    • 4
    • 3
    小鼠
    宿主
    • 14
    • 2
    • 1
    • 1
    克隆类型
    • 15
    • 3
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMBT1 antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GP340
    亚型
    IgG
    Top Product
    Discover our top product DMBT1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
    别名
    GP340 (DMBT1 产品)
    别名
    GP340 antibody, muclin antibody, CRP antibody, CRP-[a] antibody, CRP-[b] antibody, Crpd antibody, DBMT1 antibody, gp300 antibody, p80 antibody, DMBT1 antibody, gp340 antibody, deleted in malignant brain tumors 1 antibody, deleted in malignant brain tumors 1 protein antibody, gp340 antibody, deleted in malignant brain tumors 1 S homeolog antibody, DMBT1 antibody, Dmbt1 antibody, LOC100064515 antibody, dmbt1 antibody, ST201phi2-1p340 antibody, dmbt1.S antibody
    背景

    Synonyms: GP340, muclin, Deleted in malignant brain tumors 1 protein, Glycoprotein 340, Gp-340, Hensin, Salivary agglutinin, SAG, Surfactant pulmonary-associated D-binding protein, DMBT1, DMBT1/6kb.1

    Background: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.

    基因ID
    1755
    UniProt
    Q9UGM3
    途径
    Activation of Innate immune Response
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