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Crossover junction endonuclease EME1 (EME1) 抗体

EME1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN631739
发货至: 中国
  • 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
    Crossover junction endonuclease EME1 (EME1)
    适用
    • 19
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 17
    • 3
    克隆类型
    • 19
    • 1
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    非结合性
    应用范围
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purified
    免疫原
    EME1 antibody was raised using a synthetic peptide corresponding to a region with amino acids AYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRR
    Top Product
    Discover our top product EME1 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    EME1 Blocking Peptide, catalog no. 33R-1632, is also available for use as a blocking control in assays to test for specificity of this EME1 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EME1 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    Crossover junction endonuclease EME1 (EME1)
    别名
    EME1 (EME1 产品)
    别名
    6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
    背景
    EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.
    分子量
    63 kDa (MW of target protein)
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