Crossover junction endonuclease EME1 (EME1) (AA 250-330) 抗体
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Quick Overview for Crossover junction endonuclease EME1 (EME1) (AA 250-330) 抗体 (ABIN7219782)
抗原
See all Crossover junction endonuclease EME1 (EME1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-330
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原理
- Rabbit Anti-Eme1 Polyclonal Antibody
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特异性
- Eme1 Polyclonal Antibody detects endogenous levels of Eme1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Eme1 at AA range: 250-330
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Crossover junction endonuclease EME1 (EME1)
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别名
- Eme1
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背景
- EME1, MMS4, Crossover junction endonuclease EME1, MMS4 homolog, hMMS4EME1 encodes essential meiotic structure-specific endonuclease 1 that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
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分子量
- 65kD
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基因ID
- 146956
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UniProt
- Q96AY2
抗原
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