RANBP1 抗体 (C-Term)
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Quick Overview for RANBP1 抗体 (C-Term) (ABIN630712)
抗原
See all RANBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- RanBP1 antibody was raised against the C terminal of RANBP1
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纯化方法
- Affinity purified
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免疫原
- RanBP1 antibody was raised using the C terminal of RANBP1 corresponding to a region with amino acids KFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEKQ
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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RanBP1 Blocking Peptide, (ABIN939753), is also available for use as a blocking control in assays to test for specificity of this RanBP1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RANBP1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- RANBP1 (RAN Binding Protein 1 (RANBP1))
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别名
- RanBP1
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背景
- Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
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分子量
- 23 kDa (MW of target protein)
抗原
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