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RANBP1 抗体

KO Validated RANBP1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855572
发货至: 中国
  • 抗原 See all RANBP1 抗体
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    适用
    • 40
    • 21
    • 18
    • 3
    • 1
    • 1
    宿主
    • 39
    • 1
    克隆类型
    • 40
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RANBP1 antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 9
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to Ran BP1 (RAN binding protein 1)
    Ran BP1 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human RanBP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RANBP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , HeLaS3 , 293T

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chao, Lai, Lu, Lin, Mai, Huang: "NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8484-98, (2012) (PubMed).

  • 抗原
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    别名
    RAN binding protein 1 (RANBP1 产品)
    别名
    MGC64314 antibody, zeh1094 antibody, zgc:85649 antibody, hm:zeh1094 antibody, wu:fa96a09 antibody, wu:fj39g07 antibody, HTF9A antibody, Htf9a antibody, RAN binding protein 1 S homeolog antibody, RAN binding protein 1 L homeolog antibody, ran binding protein 1 antibody, RAN binding protein 1 antibody, ran-specific GTPase-activating protein pseudogene antibody, ranbp1.S antibody, ranbp1.L antibody, PVX_090070 antibody, GL50803_16969 antibody, LOC100343953 antibody, ranbp1 antibody, RANBP1 antibody, Ranbp1 antibody
    背景
    Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

    分子量
    23 kDa
    基因ID
    5902
    UniProt
    P43487
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