电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RANBP1 抗体 (N-Term)

RANBP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264631
发货至: 中国
  • 抗原 See all RANBP1 抗体
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 40
    • 20
    • 18
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 1
    克隆类型
    • 40
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RANBP1 antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 8
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    RanBP1 Antibody detects endogenous levels of total RanBP1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RanBP1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RANBP1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    别名
    RANBP1 (RANBP1 产品)
    别名
    MGC64314 antibody, zeh1094 antibody, zgc:85649 antibody, hm:zeh1094 antibody, wu:fa96a09 antibody, wu:fj39g07 antibody, HTF9A antibody, Htf9a antibody, RAN binding protein 1 S homeolog antibody, RAN binding protein 1 L homeolog antibody, ran binding protein 1 antibody, RAN binding protein 1 antibody, ran-specific GTPase-activating protein pseudogene antibody, ranbp1.S antibody, ranbp1.L antibody, PVX_090070 antibody, GL50803_16969 antibody, LOC100343953 antibody, ranbp1 antibody, RANBP1 antibody, Ranbp1 antibody
    背景

    Description: Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426). Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1 (PubMed:7882974). Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (PubMed:7882974, PubMed:7616957).

    Gene: RANBP1

    分子量
    23 kDa
    基因ID
    5902
    UniProt
    P43487
You are here:
客服