CHFR 抗体 (N-Term)
Quick Overview for CHFR 抗体 (N-Term) (ABIN630645)
抗原
See all CHFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CHFR antibody was raised against the N terminal of CHFR
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纯化方法
- Affinity purified
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免疫原
- CHFR antibody was raised using the N terminal of CHFR corresponding to a region with amino acids REWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVIN
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anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (AA 1-652) antibody
CHFR 适用: 人 ELISA, WB, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1H3-A12 unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (AA 141-422) antibodyCHFR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (AA 136-194) antibodyCHFR 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) antibodyCHFR 适用: 人, 小鼠, 大鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (AA 36-85) antibodyCHFR 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (C-Term) antibodyCHFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (C-Term) antibodyVerified CHFR 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (AA 1-290) antibodyCHFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Checkpoint with Forkhead and Ring Finger Domains (CHFR) (N-Term) antibodyCHFR 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 斑马鱼, Cow, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CHFR Blocking Peptide, (ABIN5612847), is also available for use as a blocking control in assays to test for specificity of this CHFR antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHFR antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))
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别名
- CHFR
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背景
- CHFR is an E3 ubiquitin-protein ligase required to transiently arrest cells in early prophase when they are exposed to microtubule poisons. It acts in early prophase before chromosome condensation, when the centrosome moves apart from each other along the periphery of the nucleus. CHFR probably promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress. This suggests that it may be involved in signaling the presence of mitotic stress caused by microtubule poisons.
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分子量
- 69 kDa (MW of target protein)
抗原
-
