H2AFX 抗体 (N-Term)
Quick Overview for H2AFX 抗体 (N-Term) (ABIN630601)
抗原
See all H2AFX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- H2 AFX antibody was raised against the N terminal of H2 FX
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纯化方法
- Affinity purified
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免疫原
- H2 AFX antibody was raised using the N terminal of H2 FX corresponding to a region with amino acids SGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVY
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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H2AFX Blocking Peptide, (ABIN5613915), is also available for use as a blocking control in assays to test for specificity of this H2AFX antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FX antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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别名
- H2AFX
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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分子量
- 16 kDa (MW of target protein)
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途径
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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