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FZD9 抗体

This anti-FZD9 antibody is a 兔 多克隆 antibody detecting FZD9 in WB 和 IHC. Suitable for 人 和 犬.
产品编号 ABIN630125
发货至: 中国

Quick Overview for FZD9 抗体 (ABIN630125)

抗原

See all FZD9 抗体
FZD9 (Frizzled Family Receptor 9 (FZD9))

适用

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人, 犬

宿主

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  • 1
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克隆类型

  • 57
  • 2
多克隆

标记

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This FZD9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Purified

    免疫原

    FZD9 antibody was raised using a synthetic peptide corresponding to a region with amino acids RPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDF
  • 应用备注

    WB: 2.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    FZD9 Blocking Peptide, (ABIN5613677), is also available for use as a blocking control in assays to test for specificity of this FZD9 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FZD9 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    FZD9 (Frizzled Family Receptor 9 (FZD9))

    别名

    FZD9

    背景

    FZD9 contains 1 FZ (frizzled) domain and belongs to the G-protein coupled receptor Fz/Smo family. It is receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members. It may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    分子量

    65 kDa (MW of target protein)

    途径

    WNT signaling
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