FZD9 抗体 (N-Term)
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北京 101111
Quick Overview for FZD9 抗体 (N-Term) (ABIN2776709)
抗原
See all FZD9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- FZD9 Antibody - N-terminal region
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序列
- RPPGDLGPGA GGSGTCENPE KFQYVEKSRS CAPRCGPGVE VFWSRRDKDF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against FZD9. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FZD9
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anti-Frizzled Family Receptor 9 (FZD9) antibody
FZD9 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (AA 185-270) antibodyFZD9 适用: 人 WB, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) antibodyKD Validated FZD9 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5995 unconjugated Recombinant Antibody
anti-Frizzled Family Receptor 9 (FZD9) (AA 181-230) antibodyFZD9 适用: 人, 犬, Cow, 豚鼠, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (N-Term) antibodyFZD9 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (AA 23-229) antibodyFZD9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) antibodyFZD9 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (N-Term) antibodyFZD9 适用: 人, 犬, Cow IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (AA 144-193) antibodyFZD9 适用: 人, 小鼠, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 9 (FZD9) (AA 469-591) antibodyFZD9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41253-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 3, pp. 244-53, (2010) (PubMed).
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- FZD9 (Frizzled Family Receptor 9 (FZD9))
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别名
- FZD9
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背景
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Background Information: FZD9 contains 1 FZ (frizzled) domain and belongs to the G-protein coupled receptor Fz/Smo family. It is receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members. It may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
Gene Name: Frizzled family receptor 9
Alternative Symbols: FZD3, CD349
Protein Name: Frizzled-9
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分子量
- 65kDa
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基因ID
- 8326
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NCBI登录号
- NP_003499
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UniProt
- O00144
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途径
- WNT signaling
抗原
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