电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

FEN1 抗体

FEN1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6298330
发货至: 中国
  • 抗原 See all FEN1 抗体
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    适用
    • 63
    • 43
    • 37
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 9
    克隆类型
    • 56
    • 11
    多克隆
    标记
    • 43
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FEN1 antibody is un-conjugated
    应用范围
    请咨询
    原理
    Rabbit Anti-FEN1 Antibody,
    Top Product
    Discover our top product FEN1 Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    别名
    FEN1 (FEN1 产品)
    别名
    FEN-1 antibody, FEN1 antibody, AW538437 antibody, MF1 antibody, RAD2 antibody, cb879 antibody, fen-1 antibody, fen1 antibody, mf1 antibody, rad2 antibody, xFEN1a antibody, flap structure-specific endonuclease 1 antibody, flap endonuclease 1-like antibody, Flap endonuclease-1 antibody, 5'-3' exonuclease family protein antibody, flap structure specific endonuclease 1 antibody, flap structure-specific endonuclease 1 L homeolog antibody, nuclease, Rad2 family antibody, FEN1 antibody, LOC100808044 antibody, Bm1_49605 antibody, AT5G26680 antibody, Fen1 antibody, fen1 antibody, fen1.L antibody
    背景

    Target Description: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

    Gene Symbol: FEN1

    基因ID
    2237
    UniProt
    P39748
    途径
    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
You are here:
客服