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CD25 抗体

IL2RA 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297678
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 抗体
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD25 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    原理
    Mouse anti-Human CD25 Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
    Top Product
    Discover our top product IL2RA Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    Interleukin-2 receptor subunit alpha (IL2RA 产品)
    别名
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    背景

    Target Description: Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV, Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

    Gene Symbol: IL2RA

    基因ID
    3559
    UniProt
    P01589
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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