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CD25 抗体

This anti-CD25 antibody is a 小鼠 单克隆 antibody detecting CD25 in FACS, IF 和 Func. Suitable for 人.
产品编号 ABIN6297678
发货至: 中国

Quick Overview for CD25 抗体 (ABIN6297678)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD25 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
  • 原理

    Mouse anti-Human CD25 Antibody [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.

    免疫原

    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
  • 应用备注

    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    Interleukin-2 receptor subunit alpha

    背景

    Target Description: Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV, Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

    Gene Symbol: IL2RA

    基因ID

    3559

    UniProt

    P01589

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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