Integrin beta 2 抗体
Quick Overview for Integrin beta 2 抗体 (ABIN6297676)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human CD18 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Stimulated human leukocytes were used as the immunogen for the CD18 antibody.
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免疫原
- Stimulated human leukocytes were used as the immunogen for the CD18 antibody.
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应用备注
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Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Integrin beta 2 (ITGB2)
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别名
- Integrin beta-2
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背景
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Target Description: It recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This mAb blocks these cellular interactions.
Gene Symbol: ITGB2///CD18///MFI7
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基因ID
- 3689
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UniProt
- P05107
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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