CD27 抗体
Quick Overview for CD27 抗体 (ABIN6297638)
抗原
See all CD27 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human CD27 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Sezary cells were used as the immunogen for the CD27 antibody.
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免疫原
- Sezary cells were used as the immunogen for the CD27 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD27 (CD27 Molecule (CD27))
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别名
- CD27 antigen
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背景
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Target Description: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Gene Symbol: CD27///TNFRSF7
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基因ID
- 939
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UniProt
- P26842
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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