电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

p63 抗体

This anti-p63 antibody is a 兔 多克隆 antibody detecting p63 in IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN6297602
发货至: 中国

Quick Overview for p63 抗体 (ABIN6297602)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

适用

  • 65
  • 25
  • 20
  • 5
  • 2
  • 2

宿主

  • 49
  • 23
  • 1

克隆类型

  • 42
  • 31
多克隆

标记

  • 63
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This p63 antibody is un-conjugated

应用范围

  • 46
  • 30
  • 26
  • 14
  • 14
  • 10
  • 9
  • 9
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.

    免疫原

    Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    Tumor protein 63

    背景

    Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

    基因ID

    8626

    UniProt

    Q9H3D4
You are here:
Chat with us!