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alpha Actinin 4 抗体 (N-Term)

This anti-alpha Actinin 4 antibody is a 兔 多克隆 antibody detecting alpha Actinin 4 in WB. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN629744
发货至: 中国
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Quick Overview for alpha Actinin 4 抗体 (N-Term) (ABIN629744)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

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人, 小鼠, 大鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This alpha Actinin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    Alpha Actinin 4 antibody was raised against the N terminal of ACTN4

    纯化方法

    Purified

    免疫原

    alpha Actinin 4 antibody was raised using the N terminal of ACTN4 corresponding to a region with amino acids LIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTA
  • 应用备注

    WB: 0.625 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Alpha Actinin 4 Blocking Peptide, (ABIN940431), is also available for use as a blocking control in assays to test for specificity of this Alpha Actinin 4 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ACTN4 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    alpha Actinin 4

    背景

    Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.

    分子量

    100 kDa (MW of target protein)

    途径

    Proton Transport
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