JUP 抗体
Quick Overview for JUP 抗体 (ABIN6296917)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat/Cat/Dog/Chicken/Cow Gamma Catenin Antibody / Plakoglobin [Sodium Azide Free]
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特异性
- Cell surface, cytoplasmic, cell junctions
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纯化方法
- Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
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免疫原
- Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
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应用备注
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Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- JUP (Junction Plakoglobin (JUP))
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别名
- Junction plakoglobin
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背景
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Target Description: Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]
Gene Symbol: JUP///CTNNG///DP3
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基因ID
- 3728
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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