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JUP 抗体

This anti-JUP antibody is a 小鼠 单克隆 antibody detecting JUP in WB, IF 和 IP. Suitable for 人, 小鼠, 大鼠, 小鸡, Cow, 犬 和 Cat.
产品编号 ABIN6296917
发货至: 中国

Quick Overview for JUP 抗体 (ABIN6296917)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

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人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This JUP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    Mouse anti-Human/Mouse/Rat/Cat/Dog/Chicken/Cow Gamma Catenin Antibody / Plakoglobin [Sodium Azide Free]

    特异性

    Cell surface, cytoplasmic, cell junctions

    纯化方法

    Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.

    免疫原

    Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
  • 应用备注

    Immunofluorescence: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    Immunoprecipitation: suitable

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    Junction plakoglobin

    背景

    Target Description: Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]

    Gene Symbol: JUP///CTNNG///DP3

    基因ID

    3728

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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