IGF1 抗体
Quick Overview for IGF1 抗体 (ABIN6296855)
抗原
See all IGF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat/Rabbit IGF1 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic (Secreted)
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纯化方法
- Purified human IGF1 protein was used as the immunogen for this antibody.
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免疫原
- Purified human IGF1 protein was used as the immunogen for this antibody.
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
Functional Activity: In vitro inhibition of IGF1 Activity, order BSA/azide free format -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
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别名
- Insulin-like growth factor I
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背景
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Target Description: This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Gene Symbol: IGF1///IBP1
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基因ID
- 3479
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UniProt
- P05019
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途径
- RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
抗原
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