XRCC6 抗体
Quick Overview for XRCC6 抗体 (ABIN6296746)
抗原
See all XRCC6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Mouse anti-Human/Primates Ku70 + Ku80 Antibody [Sodium Azide Free]
-
特异性
- Nuclear
-
纯化方法
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
-
免疫原
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
-
-
-
-
应用备注
-
Flow cytometry: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT -
限制
- 仅限研究用
-
-
-
缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
-
别名
- X-ray repair cross-complementing protein 6
-
背景
-
Target Description: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Gene Symbol: XRCC6///G22P1
-
基因ID
- 2547
-
UniProt
- P12956
-
途径
- DNA Damage Repair
抗原
-