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NADPH Oxidase 4 抗体

This anti-NADPH Oxidase 4 antibody is a 小鼠 单克隆 antibody detecting NADPH Oxidase 4 in WB, ELISA, FACS, IF 和 Coat. Suitable for 人.
产品编号 ABIN6296588
发货至: 中国

Quick Overview for NADPH Oxidase 4 抗体 (ABIN6296588)

抗原

See all NADPH Oxidase 4 (NOX4) 抗体
NADPH Oxidase 4 (NOX4)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NADPH Oxidase 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)
  • 原理

    Mouse anti-Human NOX4 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic and cell surface

    纯化方法

    Human recombinant protein was used as the immunogen for this NOX4 antibody.

    免疫原

    Human recombinant protein was used as the immunogen for this NOX4 antibody.
  • 应用备注

    FACS: 0.5-1 μg/10^6 cells in 0.1ml
    IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating
    WB: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    NADPH Oxidase 4 (NOX4)

    别名

    NADPH oxidase 4

    背景

    Target Description: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

    Gene Symbol: NOX4///RENOX

    基因ID

    4821

    UniProt

    Q9NPH5

    途径

    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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