NADPH Oxidase 4 抗体
Quick Overview for NADPH Oxidase 4 抗体 (ABIN6296588)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
 - Mouse anti-Human NOX4 Antibody [Sodium Azide Free]
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特异性
 - Cytoplasmic and cell surface
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纯化方法
 - Human recombinant protein was used as the immunogen for this NOX4 antibody.
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免疫原
 - Human recombinant protein was used as the immunogen for this NOX4 antibody.
 
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应用备注
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                        FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating
WB: 0.5-1 μg/mL - 
                                            
限制
 - 仅限研究用
 
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缓冲液
 - In 1X PBS, BSA free, sodium azide free
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储存液
 - Azide free
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储存条件
 - 4 °C,-20 °C
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储存方法
 - 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
 
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- NADPH Oxidase 4 (NOX4)
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别名
 - NADPH oxidase 4
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背景
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Target Description: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
Gene Symbol: NOX4///RENOX
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基因ID
 - 4821
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UniProt
 - Q9NPH5
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途径
 - Carbohydrate Homeostasis, Smooth Muscle Cell Migration
 
抗原
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