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Cyclin A 抗体

This anti-Cyclin A antibody is a 小鼠 单克隆 antibody detecting Cyclin A in IF 和 FACS. Suitable for 人, 小鼠, Cow, Green Monkey 和 Mink.
产品编号 ABIN6296265
发货至: 中国

Quick Overview for Cyclin A 抗体 (ABIN6296265)

抗原

See all Cyclin A (CCNA2) 抗体
Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

适用

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人, 小鼠, Cow, Green Monkey, Mink

宿主

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小鼠

克隆类型

  • 55
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单克隆

标记

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This Cyclin A antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Cow/African Green Monkey/Mink (Mustela) Cyclin A2 Antibody [Sodium Azide Free]

    特异性

    Predominantly nuclear

    纯化方法

    Full length bovine protein was used as the immunogen for this CCNA2 antibody.

    免疫原

    Full length bovine protein was used as the immunogen for this CCNA2 antibody.
  • 应用备注

    FACS: 0.5-1 μg/million cells
    IF: 1-2 μg/mL,

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

    别名

    Cyclin-A2

    背景

    Target Description: This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk 's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk 's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.

    Gene Symbol: CCNA2///CCN1///CCNA

    基因ID

    890

    UniProt

    P20248

    途径

    PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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