TGFB1 抗体
Quick Overview for TGFB1 抗体 (ABIN6296206)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Monkey/Cow/Dog/Mouse/Rat/Hamster TGF-beta Antibody [Sodium Azide Free]
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特异性
- Cytoplasm and extracellular (secreted)
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纯化方法
- Bovine TGF-beta2 protein was used as the immunogen for the TGF-beta antibody.
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免疫原
- Bovine TGF-beta2 protein was used as the immunogen for the TGF-beta antibody.
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anti-Transforming Growth Factor, beta 1 (TGFB1) (C-Term) antibody
TGFB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 62-195) antibodyTGFB1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7F6 unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 351-390) antibodyTGFB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibodyTGFB1 适用: 小鼠, 大鼠, Cow, Pig, 绵羊, 豚鼠, 犬, 马, 山羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 62-195) antibodyTGFB1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (N-Term) antibodyTGFB1 适用: 人 WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (C-Term) antibodyTGFB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibodyTGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D11 unconjugated
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应用备注
- Functional Activity: Cytokine Neutralization (Order SAF formulation)
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限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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别名
- Transforming growth factor beta-1 ]
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背景
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Target Description: This mAb recognizes TGF beta 1, 2 and 3. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGFb's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
Gene Symbol: TGFB1///TGFB///TGFB3///TGFB2
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UniProt
- P01137, P10600, P61812
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途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
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