MUC5AC 抗体
Quick Overview for MUC5AC 抗体 (ABIN6296194)
抗原
See all MUC5AC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Mouse anti-Human/Monkey/Rabbit/Cat/Mouse/Rat/Cow/Chicken MUC5AC Antibody [Sodium Azide Free]
-
特异性
- Cytoplasmic
-
纯化方法
- An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for the MUC5AC antibody.
-
免疫原
- An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for the MUC5AC antibody.
-
-
-
-
应用备注
-
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT -
限制
- 仅限研究用
-
-
-
缓冲液
- In 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
-
别名
- Mucin-5AC
-
背景
-
Target Description: This mAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. mAb 1-13M1 pairs with mAb 9-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Gene Symbol: MUC5AC///MUC5
-
基因ID
- 4586
-
UniProt
- P98088
抗原
-