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S100A8 抗体

This anti-S100A8 antibody is a 小鼠 单克隆 antibody detecting S100A8 in IHC, IF 和 FACS. Suitable for 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, Cat, 猴, 马, 豚鼠, Baboon 和 山羊.
产品编号 ABIN6296169
发货至: 中国

Quick Overview for S100A8 抗体 (ABIN6296169)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, Cat, 猴, 马, 豚鼠, Baboon, 山羊

宿主

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小鼠

克隆类型

  • 121
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单克隆

标记

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This S100A8 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Baboon/Monkey/Cow/Pig/Goat/Horse/Cat/Dog/Rabbit/Guinea Pig/Rat/Mouse Macrophage Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.

    免疫原

    An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    Protein S100-A8

    背景

    Target Description: Recognizes the macrophage L1 protein Calprotectin, expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.

    Gene Symbol: S100A8///CAGA///CFAG///MRP8///S100A9///CAGB///CFAG///MRP14

    UniProt

    P05109, P06702

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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