AMACR 抗体
Quick Overview for AMACR 抗体 (ABIN6296086)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human AMACR / p504S Antibody (Prostate Cancer Marker) [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- A recombinant human protein was used as the immunogen for the AMACR antibody.
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免疫原
- A recombinant human protein was used as the immunogen for the AMACR antibody.
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应用备注
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Immunohistology (FFPE): 1-2 μg/mL for 30 minutes at RT
IF: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In sterile PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- Alpha-methylacyl-CoA racemase
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背景
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Target Description: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Gene Symbol: AMACR
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基因ID
- 23600
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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