Calnexin 抗体
Quick Overview for Calnexin 抗体 (ABIN6296055)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Calnexin Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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免疫原
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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应用备注
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WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/10^6 cells
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Calnexin (CANX)
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别名
- Calnexin
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背景
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Target Description: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Gene Symbol: CANX
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基因ID
- 821
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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