Nkx2-2 抗体
Quick Overview for Nkx2-2 抗体 (ABIN6296003)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti-Human NKX2.2 Antibody [Sodium Azide Free]
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特异性
- Nuclear
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纯化方法
- A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
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免疫原
- A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
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应用备注
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FACS: 0.5-1 μg/10e6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- Homeobox protein Nkx-2.2
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背景
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Target Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
Gene Symbol: NKX2-2///NKX2.2///NKX2B
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基因ID
- 4821
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UniProt
- O95096
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途径
- Dopaminergic Neurogenesis
抗原
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