XRCC6 抗体
Quick Overview for XRCC6 抗体 (ABIN6295976)
抗原
See all XRCC6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Ku70 + Ku80 Antibody [Sodium Azide Free]
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特异性
- Nuclear
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纯化方法
- A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
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免疫原
- A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
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应用备注
- Flow cytometry: 0.5-1 μg/10e6 cells
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限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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别名
- X-ray repair cross-complementing protein 6
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背景
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Target Description: Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]
Gene Symbol: XRCC6///G22P1
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基因ID
- 2547
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UniProt
- P12956
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途径
- DNA Damage Repair
抗原
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