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Tyrosinase-Related Protein 1 抗体

This anti-Tyrosinase-Related Protein 1 antibody is a 小鼠 单克隆 antibody detecting Tyrosinase-Related Protein 1 in IHC, IF 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN6295921
发货至: 中国
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (ABIN6295921)

抗原

See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
Tyrosinase-Related Protein 1 (TYRP1)

适用

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人, 小鼠

宿主

  • 113
  • 42
  • 1
小鼠

克隆类型

  • 86
  • 68
  • 2
单克隆

标记

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This Tyrosinase-Related Protein 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse TRP1 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

    免疫原

    Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Tyrosinase-Related Protein 1 (TYRP1)

    别名

    5,6-dihydroxyindole-2-carboxylic acid oxidase

    背景

    Target Description: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

    Gene Symbol: TYRP1///CAS2///TYRP///TYRRP

    基因ID

    7306

    UniProt

    P17643
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