Tyrosinase-Related Protein 1 抗体
Quick Overview for Tyrosinase-Related Protein 1 抗体 (ABIN6295921)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse TRP1 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
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免疫原
- Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
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背景
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Target Description: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Gene Symbol: TYRP1///CAS2///TYRP///TYRRP
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基因ID
- 7306
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UniProt
- P17643
抗原
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