电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

JUP 抗体 (N-Term)

This anti-JUP antibody is a 小鼠 单克隆 antibody detecting JUP in WB, IF 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN6295501
发货至: 中国

Quick Overview for JUP 抗体 (N-Term) (ABIN6295501)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

  • 172
  • 72
  • 64
  • 35
  • 27
  • 25
  • 24
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 102
  • 70
  • 2
  • 1
小鼠

克隆类型

  • 92
  • 83
单克隆

标记

  • 75
  • 12
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This JUP antibody is un-conjugated

应用范围

  • 113
  • 70
  • 51
  • 41
  • 33
  • 26
  • 26
  • 23
  • 18
  • 16
  • 10
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 15
    • 11
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Mouse anti-Human/Mouse Gamma Catenin Antibody / Plakoglobin [Sodium Azide Free]

    特异性

    Cell surface, cytoplasmic, cell junctions

    纯化方法

    Recombinant full length human gamma Catenin fused to maltose binding protein was used as the immunogen for the Plakoglobin antibody. The epitope has been found to be in the N-terminal region.

    免疫原

    Recombinant full length human gamma Catenin fused to maltose binding protein was used as the immunogen for the Plakoglobin antibody. The epitope has been found to be in the N-terminal region.
  • 应用备注

    Immunofluorescence: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    Immunoprecipitation: suitable

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    Junction plakoglobin

    背景

    Target Description: It recognizes a protein of 80-87 kDa, identified as gamma-Catenin or Plakoglobin. The catenins (alpha, beta, gamma and δ,) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

    Gene Symbol: JUP///CTNNG///DP3

    基因ID

    3728

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
You are here:
Chat with us!