PODXL 抗体 (Extracellular Domain)
Quick Overview for PODXL 抗体 (Extracellular Domain) (ABIN6295450)
抗原
See all PODXL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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原理
- Mouse anti-Human/Rabbit/Rat Podocalyxin Antibody [Sodium Azide Free]
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特异性
- Cell surface and cytoplasmic
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纯化方法
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
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免疫原
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IP: 1-2 μg/500 μg protein
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- Podocalyxin
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背景
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Target Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Gene Symbol: PODXL///PCLP///PCLP1
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基因ID
- 5420
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UniProt
- O00592
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途径
- Tube Formation
抗原
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