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GJB1 抗体 (Cytoplasmic Loop)

This anti-GJB1 antibody is a 小鼠 单克隆 antibody detecting GJB1 in WB, IHC, IF 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6295447
发货至: 中国

Quick Overview for GJB1 抗体 (Cytoplasmic Loop) (ABIN6295447)

抗原

See all GJB1 抗体
GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

适用

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人, 大鼠, 小鼠

宿主

  • 55
  • 26
  • 12
小鼠

克隆类型

  • 54
  • 39
单克隆

标记

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This GJB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    Cytoplasmic Loop

    原理

    Mouse anti-Rat/Mouse/Human Connexin 32 Antibody / GJB1 [Sodium Azide Free]

    特异性

    Cell surface, cytoplasmic

    纯化方法

    Rat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1).

    免疫原

    Rat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1).
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IHC (Frozen): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

    别名

    Gap junction beta-1 protein

    背景

    Target Description: This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another.

    Gene Symbol: GJB1///CX32

    基因ID

    2705

    UniProt

    P08034

    途径

    Cell-Cell Junction Organization
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