PINK1 抗体 (Center)
Quick Overview for PINK1 抗体 (Center) (ABIN6295262)
抗原
See all PINK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 237-266, Center
-
原理
- Rabbit Anti-PINK1 (PARK6) (Center) Antibody
-
免疫原
- This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6).
-
-
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
-
别名
- PINK1
-
背景
-
Target Description: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Gene Symbol: PINK1
-
基因ID
- 65018
-
UniProt
- Q9BXM7
-
途径
- Autophagy
抗原
-