p63 抗体 (AA 5-17)
Quick Overview for p63 抗体 (AA 5-17) (ABIN6294546)
抗原
See all p63 (TP63) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-17
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原理
- Rabbit anti-Human/Mouse/Rat/Cow p40 Antibody [Sodium Azide Free]
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特异性
- Nuclear
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纯化方法
- Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.
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免疫原
- Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.
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应用备注
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FACS: 0.5-1 μg/10e6 cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- p63 (TP63) (Tumor Protein P63 (TP63))
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别名
- Tumor protein 63
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背景
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Target Description: p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p40 antibody 's ability to distinguish between the tumor types appears to be superior when compared to p63. The ability to utilize a p40 antibody probe as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L
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基因ID
- 8626
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UniProt
- Q9H3D4
抗原
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