Topoisomerase II alpha 抗体 (AA 1352-1493)
Quick Overview for Topoisomerase II alpha 抗体 (AA 1352-1493) (ABIN6294307)
抗原
See all Topoisomerase II alpha (TOP2A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1352-1493
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原理
- Mouse anti-Human/Mouse TOP2A Antibody / Topoisomerase II alpha [Sodium Azide Free]
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特异性
- Nuclear
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纯化方法
- Amino acids 1352-1493 from the human protein were used as the immunogen for this Topoisomerase II alpha antibody.
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免疫原
- Amino acids 1352-1493 from the human protein were used as the immunogen for this Topoisomerase II alpha antibody.
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应用备注
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FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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别名
- DNA topoisomerase 2-alpha
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背景
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Target Description: This mAb recognizes an ~170 kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.
Gene Symbol: TOP2A///TOP2
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基因ID
- 7153
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UniProt
- P11388
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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