POMC 抗体 (AA 1-24)
Our Local Distributor
北京 101111
Quick Overview for POMC 抗体 (AA 1-24) (ABIN6294239)
抗原
See all POMC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-24
-
原理
- Mouse anti-Human/Mouse/Rat ACTH Antibody [Sodium Azide Free]
-
特异性
- Cytoplasmic
-
纯化方法
- A synthetic peptide corresponding to aa 1-24 of human ACTH was used as the immunogen for this antibody.
-
免疫原
- A synthetic peptide corresponding to aa 1-24 of human ACTH was used as the immunogen for this antibody.
-
-
anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (N-Term) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC, ELISA, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal 57 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) antibodyPOMC 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 205-267) antibodyPOMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated
anti-Proopiomelanocortin (POMC) (AA 138-176), (Middle Region) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: order BSA-free format for coating
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1) -
限制
- 仅限研究用
-
-
-
缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- POMC (Proopiomelanocortin (POMC))
-
别名
- Pro-opiomelanocortin , Beta-endorphin, Met-enkephalin]
-
背景
-
Target Description: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific post-translational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH (also called Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This antibody is specific to Synacthen (aa 1-24 of ACTH) and does not react with CLIP (aa 17-39 of ACTH). ACTH is produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. ACTH antibody is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
Gene Symbol: POMC
-
基因ID
- 5443
-
UniProt
- P01189
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
抗原
-
