ABCB11 抗体
Quick Overview for ABCB11 抗体 (ABIN6291730)
抗原
See all ABCB11 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purification
-
免疫原
- A synthetic peptide of human ABCB11
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000
-
说明
-
Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20C. Avoid freeze / thaw cycles.
-
-
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
-
别名
- ABCB11
-
背景
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
-
分子量
- 146.407 kDa
-
基因ID
- 8647
-
UniProt
- O95342
抗原
-