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Pleiotrophin 抗体 (C-Term)

This anti-Pleiotrophin antibody is a 兔 多克隆 antibody detecting Pleiotrophin in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6266311
发货至: 中国
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Quick Overview for Pleiotrophin 抗体 (C-Term) (ABIN6266311)

抗原

See all Pleiotrophin (PTN) 抗体
Pleiotrophin (PTN)

适用

  • 86
  • 57
  • 50
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 101
  • 10
  • 2
  • 2

克隆类型

  • 93
  • 22
多克隆

标记

  • 42
  • 14
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Pleiotrophin antibody is un-conjugated

应用范围

  • 73
  • 26
  • 26
  • 25
  • 25
  • 18
  • 16
  • 9
  • 6
  • 6
  • 5
  • 3
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    PTN Antibody detects endogenous levels of total PTN.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PTN, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Pleiotrophin (PTN)

    别名

    PTN

    背景

    Description: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

    Gene: PTN

    分子量

    19kDa

    基因ID

    5764

    UniProt

    P21246

    途径

    RTK signaling
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