TCF7 抗体 (N-Term)
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北京 101111
Quick Overview for TCF7 抗体 (N-Term) (ABIN6266277)
抗原
See all TCF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- TCF7 Antibody
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特异性
- TCF7 Antibody detects endogenous levels of total TCF7
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预测反应
- Pig,Bovine,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human TCF7, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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别名
- TCF7
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背景
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Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Gene: TCF7
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分子量
- 42kDa
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基因ID
- 6932
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UniProt
- P36402
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途径
- WNT signaling
抗原
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